⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611721 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL8188453 | 0.65 | — | — | |
| SCHEMBL1259184 | 0.62 | — | — | |
| SCHEMBL28195765 | 0.62 | — | — | |
| SCHEMBL1091034 | 0.62 | — | — | |
| SCHEMBL8471071 | 0.62 | — | — | |
| SCHEMBL11117919 | 0.60 | — | — | |
| SCHEMBL27629163 | 0.60 | — | — | |
| SCHEMBL13631409 | 0.60 | — | — | |
| SCHEMBL28884779 | 0.60 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562052-B2 | Bicyclicpyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2017-02-07 | — | — | US | claimed |
| EP-2888245-B1 | NEW BICYCLICPYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-09-21 | — | — | EP | claimed |
| US-20150368256-A1 | NEW BICYCLICPYRIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2015-12-24 | — | — | US | claimed |
| EP-2888245-A1 | NEW BICYCLICPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2015-07-01 | — | — | EP | claimed |
| WO-2014029723-A1 | NEW BICYCLICPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-02-27 | — | — | WO | claimed |
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | claimed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | claimed |
| EP-2417121-A1 | 4, 5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | Pfizer Inc. (US) | 2012-02-15 | — | — | EP | claimed |
| US-20120022058-A1 | 4,5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | PFIZER INC. | 2012-01-26 | — | — | US | claimed |
| US-7879167-B2 | Tetrazole amide such as 5-formamido-1H-tetrazole and an oxidizer such as phase stabilized ammonium nitrate (PSAN); tetrazole amide has greater stability with the preferred oxidizer; air bags | TK HOLDINGS, INC. (US) | 2011-02-01 | — | — | US | claimed |
| EP-0015065-B1 | PYRAZOLO (5,1-B) QUINAZOLIN-9(4H)-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1983-12-28 | — | — | EP | claimed |
| US-4419352-A | ANTIALLERGENS; ANTI SECRETORY AGENTS; MUCUS | FISONS LIMITED (GB) | 1983-12-06 | — | — | US | claimed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | claimed |
| EP-0080176-A1 | Triazoloquinazolines, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1983-06-01 | — | — | EP | claimed |
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | claimed |
| US-4333934-A | ANTIALLERGIC ACTIVITY | ROUSSEL UCLAF (FR) | 1982-06-08 | — | — | US | claimed |
| US-4297355-A | (1H,3H,5H)-(1)-Benzopyrano-(2,3-d)-pyrimidine-4-one-2-thiones and their use as anti-allergy agents | SCHERING CORPORATION (US) | 1981-10-27 | — | — | US | claimed |
| US-4281008-A | Pharmaceutical heterocyclic compounds and compositions | FISONS LIMITED (GB) | 1981-07-28 | — | — | US | claimed |
| EP-0017332-A1 | Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them | FISONS plc (GB) | 1980-10-15 | — | — | EP | claimed |
| US-4228173-A | Thiopyrano-benzopyrans, compositions and method of use thereof | FISONS LIMITED (GB) | 1980-10-14 | — | — | US | claimed |