Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 17/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 15/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633993 | 0.94 | F11 (0.47) | F11KLKB1FFAR2NOS2NOS3 | |
| SCHEMBL3634248 | 0.84 | F11 (0.57) | F11KLKB1 | |
| SCHEMBL3636481 | 0.83 | F11 (0.54) | F11KLKB1 | |
| SCHEMBL3635061 | 0.82 | F11 (0.51) | F11KLKB1NOS2NOS3NOS1 | |
| SCHEMBL3632133 | 0.82 | F11 (0.58) | F11KLKB1F10PLAT | |
| SCHEMBL3633421 | 0.81 | F11 (0.65) | F11KLKB1F10PLAT | |
| SCHEMBL3635449 | 0.81 | F11 (0.57) | F11KLKB1 | |
| SCHEMBL3635497 | 0.81 | F11 (0.45) | F11KLKB1 | |
| SCHEMBL3003352 | 0.80 | F11 (0.71) | F11KLKB1F10PLAT | |
| SCHEMBL3003355 | 0.80 | F11 (0.71) | F11KLKB1F10PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |