Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 12/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593000 | 0.80 | XPO1 (0.48) | XPO1TRPV1CYP11B1CYP11B2PTGS2 | |
| SCHEMBL1593002 | 0.78 | XPO1 (0.44) | XPO1TRPV1CYP11B1CYP11B2KDM1A | |
| SCHEMBL1592494 | 0.71 | XPO1 (0.51) | XPO1PTGS2 | |
| SCHEMBL1592486 | 0.71 | XPO1 (0.48) | XPO1ALDH1A1 | |
| SCHEMBL30176895 | 0.69 | XPO1 (0.34) | XPO1TRPV1CYP11B1CYP11B2 | |
| SCHEMBL30346302 | 0.68 | XPO1 (0.63) | XPO1TRPV1CYP11B2GAA | |
| SCHEMBL1592487 | 0.68 | XPO1 (0.43) | XPO1TRPV1 | |
| SCHEMBL1592440 | 0.65 | XPO1 (0.47) | XPO1 | |
| SCHEMBL1592800 | 0.64 | XPO1 (0.48) | XPO1PTGS2 | |
| SCHEMBL20880362 | 0.62 | XPO1 (0.54) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152692-A2 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | Canbas Co. Ltd. (JP) | 2010-02-17 | — | — | EP | claimed |
| WO-2009031040-A2 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO., LTD. (JP) | 2009-03-12 | — | — | WO | claimed |