Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 6/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593002 | 0.75 | XPO1 (0.44) | XPO1TRPV1CYP11B1CYP11B2ACHE | |
| SCHEMBL1593000 | 0.72 | XPO1 (0.48) | XPO1TRPV1CYP11B1CYP11B2 | |
| SCHEMBL3636175 | 0.69 | XPO1 (0.40) | XPO1TRPV1CYP11B1CYP11B2 | |
| SCHEMBL30176857 | 0.68 | RORC (0.33) | GRM2 | |
| SCHEMBL30176863 | 0.67 | XPO1 (0.49) | XPO1TRPV1 | |
| SCHEMBL1592522 | 0.65 | XPO1 (0.47) | XPO1ACHE | |
| SCHEMBL30346433 | 0.64 | — | — | |
| SCHEMBL1592487 | 0.64 | XPO1 (0.43) | XPO1TRPV1 | |
| SCHEMBL29934324 | 0.63 | XPO1 (0.43) | XPO1TRPV1 | |
| SCHEMBL26170324 | 0.63 | ALDH1A1 (0.41) | TRPV1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125872-A1 | SUBSTITUTED AZOLE DIONE COMPOUNDS WITH ANTIVIRAL ACTIVITY | Stemline Therapeutics Inc. (US) | 2023-02-08 | — | — | EP | disclosed |