Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595309 | 0.91 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL595685 | 0.90 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL13229248 | 0.90 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3636503 | 0.89 | DGAT1 (0.84) | DGAT1 | |
| SCHEMBL595461 | 0.89 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL595596 | 0.89 | DGAT1 (0.86) | DGAT1 | |
| Hydrochloric Acid SCHEMBL594449 | 0.88 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL594663 | 0.87 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL13895474 | 0.87 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL595631 | 0.87 | DGAT1 (0.72) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155687-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008141976-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |