Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739759 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL31498242 | 0.84 | MGAM (0.61) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL7565802 | 0.84 | MGAM (0.61) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL27418511 | 0.82 | MAPT (0.54) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL29519324 | 0.82 | MAPT (0.54) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL6786850 | 0.81 | HTT (0.68) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL3638626 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL9095415 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL11500721 | 0.81 | MAPT (0.68) | ALDH1A1MAPTHPGDGLAACHE | |
| SCHEMBL27533701 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178843-A2 | NEW LIGANDS OF THE BENZO[H]QUINOLINE CLASS AND TRANSITION METAL COMPLEXES CONTAINING THEM AND USE OF SAID COMPLEXES AS CATALYST | UNIVERSITA' DEGLI STUDI DI UDINE (IT) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009007443-A2 | NEW LIGANDS OF THE BENZO[H]QUINOLINE CLASS AND TRANSITION METAL COMPLEXES CONTAINING THEM AND USE OF SAID COMPLEXES AS CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE (IT) | 2009-01-15 | — | — | WO | disclosed |