Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643241 | 0.93 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL3770446 | 0.93 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL4750093 | 0.92 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL3637166 | 0.91 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL3639151 | 0.91 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL3780666 | 0.90 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL3638491 | 0.90 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL3777190 | 0.89 | REN (0.71) | RENCYP3A4 | |
| SCHEMBL3777196 | 0.89 | REN (0.71) | RENCYP3A4 | |
| SCHEMBL3777769 | 0.89 | REN (0.71) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167609-A1 | RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2010-03-31 | — | — | EP | claimed |
| WO-2009096996-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-06 | — | — | WO | claimed |
| EP-2167609-A1 | RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009096996-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-06 | — | — | WO | disclosed |