Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 11/20 | 0.32 |
| ▸ | CA2 | P00918 | 11/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL16700581 | 0.86 | NPC1 (0.42) | NPC1POLBRAB9ASMN1; SMN2KCNH2 | |
| SCHEMBL29252549 | 0.79 | SMN1; SMN2 (0.47) | NPC1POLBRAB9ASMN1; SMN2CA1 | |
| SCHEMBL15670987 | 0.77 | CA2 (0.34) | CA1CA2KCNH2MMP1MMP2 | |
| SCHEMBL5700786 | 0.77 | CA1 (0.30) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30081384 | 0.76 | GGPS1 (0.36) | KCNH2KMT2A | |
| SCHEMBL3312380 | 0.76 | GGPS1 (0.36) | KCNH2KMT2A | |
| SCHEMBL17162135 | 0.75 | — | — | |
| Trifluoroacetic Acid SCHEMBL16700997 | 0.74 | SMN1; SMN2 (0.42) | NPC1POLBRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL627705 | 0.73 | — | — | |
| SCHEMBL29822577 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164935-A1 | LUBRICATING GREASE COMPOSITION | Klüber Lubrication München KG (DE) | 2010-03-24 | — | — | EP | claimed |
| WO-2008154997-A1 | LUBRICATING GREASE COMPOSITION | KLüBER LUBRICATION MüNCHEN KG (DE) | 2008-12-24 | — | — | WO | claimed |