SCHEMBL363693

SCHEMBL363693

[O]c1ccccc1-c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.52
KIF11 P52732 8/20 0.49
ALDH1A1 P00352 3/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TNKS2 Q9H2K2 2/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19541233 0.87 AHR (0.61) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL417016 0.84 AHR (0.57) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL5488320 0.82 AHR (0.55) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL19442036 0.81 AHR (0.70) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL5999272 0.81 AHR (0.70) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL29742954 0.81 AHR (0.70) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL19928476 0.79 AHR (0.52) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL3273641 0.79 AHR (0.52) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL3275194 0.79 KIF11 (0.58) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL17468647 0.79 AHR (0.52) AHRKIF11ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448925-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS Nitto Denko Corporation (JP) 2012-05-09 EP disclosed
WO-2012009283-A1 PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 WO disclosed
WO-2011008560-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2011-01-20 WO disclosed