Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637013 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL4881131 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL3636587 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL3640446 | 0.86 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL7312772 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2PPARG | |
| SCHEMBL7299305 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2PPARG | |
| SCHEMBL3636583 | 0.86 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL8847521 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL3634917 | 0.85 | PPARG (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9045249 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162442-B1 | DUAL-ACTING BENZOIMIDAZOLE ANTIHYPERTENSIVE AGENTS | THERAVANCE INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2162442-A1 | DUAL-ACTING BENZOIMIDAZOLE ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008153857-A1 | DUAL-ACTING BENZOIMIDAZOLE ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2008-12-18 | — | — | WO | disclosed |