Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056256 | 0.93 | NOS1 (0.48) | NOS1NOS2 | |
| SCHEMBL4059958 | 0.88 | NOS1 (0.48) | NOS1NOS2 | |
| SCHEMBL3636427 | 0.71 | CYP1A2 (0.38) | NOS1NOS2 | |
| SCHEMBL2784950 | 0.69 | — | — | |
| SCHEMBL385765 | 0.69 | — | — | |
| SCHEMBL2265669 | 0.69 | — | — | |
| SCHEMBL384800 | 0.69 | — | — | |
| SCHEMBL664855 | 0.69 | — | — | |
| SCHEMBL2788493 | 0.69 | — | — | |
| SCHEMBL75987 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170875-A1 | AMINOALKYLAZOLE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | Wyeth LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009012252-A1 | AMINOALKYLAZOLE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |