Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980018 | 0.83 | SIGMAR1 (0.55) | SIGMAR1EPHX2TNIKHRH3POLB | |
| SCHEMBL15137345 | 0.81 | SIGMAR1 (0.57) | SIGMAR1EPHX2HRH3POLBL3MBTL3 | |
| SCHEMBL13283790 | 0.80 | SIGMAR1 (0.53) | SIGMAR1EPHX2TNIKHRH3POLB | |
| SCHEMBL8009145 | 0.80 | SIGMAR1 (0.55) | SIGMAR1EPHX2TNIKHRH3POLB | |
| SCHEMBL9069989 | 0.80 | SIGMAR1 (0.77) | SIGMAR1HRH3SMN1; SMN2 | |
| SCHEMBL5785769 | 0.79 | GAA (0.60) | SIGMAR1EPHX2HRH3ALDH1A1LMNA | |
| SCHEMBL65840 | 0.79 | SMN1; SMN2 (0.62) | ALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL28069120 | 0.79 | KDM4E (0.59) | EPHX2HRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14100178 | 0.79 | EPHX2 (0.50) | SIGMAR1EPHX2HRH3ALDH1A1LMNA | |
| SCHEMBL12606897 | 0.79 | SIGMAR1 (0.51) | SIGMAR1EPHX2TNIKHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |