Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636646 | 0.93 | P2RX3 (1.00) | P2RX3CYP2C9 | |
| SCHEMBL4235279 | 0.92 | P2RX3 (1.00) | P2RX3CYP2C9 | |
| SCHEMBL4228769 | 0.92 | P2RX3 (0.87) | P2RX3CYP2C9 | |
| SCHEMBL3639545 | 0.91 | P2RX3 (0.85) | P2RX3CYP2C9 | |
| SCHEMBL4238916 | 0.91 | P2RX3 (1.00) | P2RX3CYP2C9 | |
| SCHEMBL3638923 | 0.90 | P2RX3 (0.75) | P2RX3CYP2C9 | |
| SCHEMBL4235654 | 0.90 | P2RX3 (0.82) | P2RX3CYP2C9 | |
| SCHEMBL3636551 | 0.89 | P2RX3 (0.81) | P2RX3CYP2C9 | |
| SCHEMBL3640543 | 0.89 | P2RX3 (0.81) | P2RX3CYP2C9 | |
| SCHEMBL3638498 | 0.88 | P2RX3 (0.92) | P2RX3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155751-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AstraZeneca AB (SE) | 2010-02-24 | — | — | EP | claimed |
| WO-2008136756-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | WO | claimed |
| EP-2155751-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AstraZeneca AB (SE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008136756-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | WO | disclosed |