Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | GLA | P06280 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645121 | 0.86 | KDM4E (0.64) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3638559 | 0.83 | L3MBTL1 (0.72) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3637720 | 0.82 | L3MBTL1 (0.69) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3644032 | 0.79 | CTNNB1 (0.50) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3640302 | 0.79 | L3MBTL1 (0.72) | KDM4EGAAGLAHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3640232 | 0.78 | HPGD (0.70) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3640031 | 0.77 | PDE5A (0.69) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3675539 | 0.76 | L3MBTL1 (0.80) | KDM4EGAAGLAHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3670729 | 0.75 | L3MBTL1 (0.78) | KDM4EGAAGLAHSD17B10HPGD | |
| SCHEMBL3778305 | 0.75 | KDM4E (0.65) | KDM4EGAAGLAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173346-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | Summit Corporation Plc (GB) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009001060-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | SUMMIT CORPORATION PLC (GB) | 2008-12-31 | — | — | WO | disclosed |