Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016767 | 0.80 | JAK2 (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL2016462 | 0.75 | JAK2 (0.35) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL21811702 | 0.73 | TLR4 (0.34) | — | |
| SCHEMBL3635660 | 0.72 | JAK2 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL2016740 | 0.71 | JAK2 (0.35) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL3639515 | 0.70 | CA1 (0.35) | — | |
| SCHEMBL2020686 | 0.69 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL2018153 | 0.68 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL11985369 | 0.67 | JAK2 (0.33) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL11985370 | 0.67 | DRD2 (0.35) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162429-A2 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009005110-A2 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-08 | — | — | WO | disclosed |