Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887543 | 0.82 | KDM4E (0.32) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL3589189 | 0.82 | KDM4E (0.32) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL813890 | 0.79 | KDM4E (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL15542332 | 0.79 | KDM4E (0.42) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL31375665 | 0.78 | — | — | |
| SCHEMBL4835506 | 0.78 | ACE (0.42) | KMT2ACYP2D6SMN1; SMN2 | |
| SCHEMBL11818645 | 0.78 | — | — | |
| SCHEMBL31022855 | 0.76 | KDM4E (0.41) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL28544765 | 0.76 | KDM4E (0.34) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL11818658 | 0.76 | ACE (0.41) | KMT2ACYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192360-A1 | METHODS OF TREATING A SUBJECT FOR POST-TREATMENT LYME DISEASE (PTLD) AND COMPOSITIONS FOR USE IN THE SAME | INCELLDX, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| EP-2164491-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | Euroscreen S.A. (BE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009010477-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009010479-A2 | HETEROCYCLIC METHYLENE PIPERIDINE DERIVATIVES AND THEIR USE | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |