SCHEMBL3638043

SCHEMBL3638043

COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(CNC(=O)[C@@H]2CCCNC2)c2c[nH]c3ccccc23)c(OC)c1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635066 0.94 GHSR (0.76) GHSR
SCHEMBL20525990 0.90 GHSR (0.77) GHSR
SCHEMBL3636896 0.89 GHSR (0.75) GHSR
SCHEMBL3636549 0.89 GHSR (0.68) GHSR
SCHEMBL3638041 0.87 GHSR (1.00) GHSR
SCHEMBL3678888 0.87 GHSR (1.00) GHSR
SCHEMBL3638039 0.87 GHSR (1.00) GHSR
SCHEMBL3634643 0.85 GHSR (0.75) GHSR
SCHEMBL20525892 0.84 GHSR (0.80) GHSR
SCHEMBL20525911 0.84 GHSR (0.81) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155227-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION Dickson, Suzanne L (SE) 2010-02-24 — — EP disclosed
WO-2009020419-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION DICKSON SUZANNE L (SE) 2009-02-12 — — WO disclosed
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