SCHEMBL3638665

SCHEMBL3638665

COc1ccc(Cn2c(CCCc3ccccc3)nnc2C(CNC(=O)C(C)(C)N)c2c[nH]c3ccccc23)cc1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20525904 1.00 GHSR (0.73) GHSR
SCHEMBL3636539 0.92 GHSR (0.70) GHSR
SCHEMBL3631271 0.89 GHSR (0.73) GHSR
SCHEMBL3637139 0.87 GHSR (0.70) GHSR
SCHEMBL20525910 0.87 GHSR (0.70) GHSR
SCHEMBL3639660 0.87 GHSR (0.70) GHSR
SCHEMBL3636024 0.87 GHSR (0.70) GHSR
SCHEMBL3635561 0.85 GHSR (0.67) GHSR
SCHEMBL3634540 0.85 GHSR (0.71) GHSR
SCHEMBL20525912 0.85 GHSR (0.74) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155227-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION Dickson, Suzanne L (SE) 2010-02-24 — — EP disclosed
WO-2009020419-A1 NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION DICKSON SUZANNE L (SE) 2009-02-12 — — WO disclosed
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