SCHEMBL3638671

SCHEMBL3638671

CC(C)Cc1nc(NN2C(=O)CC(C)(C)C2=O)ccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XPO1 O14980 11/20 0.40
AR P10275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1592372 0.79 XPO1 (0.47) XPO1
SCHEMBL1592374 0.78 XPO1 (0.43) XPO1
SCHEMBL3636175 0.76 XPO1 (0.40) XPO1AR
SCHEMBL24465034 0.66 XPO1 (0.53) XPO1
SCHEMBL18191820 0.66 XPO1 (0.48) XPO1
SCHEMBL8141359 0.64 XPO1 (0.58) XPO1
SCHEMBL18197803 0.63 KDM4E (0.39)
SCHEMBL1593014 0.61 XPO1 (0.46) XPO1
SCHEMBL1593015 0.61 XPO1 (0.42) XPO1
SCHEMBL1593192 0.60 XPO1 (0.41) XPO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152692-A2 COMPOUNDS WITH ANTI-CANCER ACTIVITY Canbas Co. Ltd. (JP) 2010-02-17 EP claimed
WO-2009031040-A2 COMPOUNDS WITH ANTI-CANCER ACTIVITY CANBAS CO., LTD. (JP) 2009-03-12 WO claimed