SCHEMBL3638765

SCHEMBL3638765

C=CC(=O)C(CC)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.46
AKR1A1 P14550 1/20 0.46
CHRM3 P20309 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
ADRA1A P35348 1/20 0.46
HRH1 P35367 1/20 0.46
DRD3 P35462 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 6/20 0.44
CYP3A4 P08684 2/20 0.44
NFKB1 P19838 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HDAC7 Q8WUI4 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743001 0.91 HDAC1 (0.50) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL30924819 0.87 CA2 (0.57) TSHRCA2MAPK1CA1ALDH1A1
SCHEMBL812136 0.85
SCHEMBL26575537 0.81 HDAC1 (0.50) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL30820553 0.81 CA2 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL16374300 0.81 TSHR (0.35) TSHRCA2MAPK1CA1ALDH1A1
SCHEMBL10526621 0.77 GRIK1 (0.39) TSHRCA2MAPK1CA1ALDH1A1
SCHEMBL8079206 0.76 TSHR (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
Propene SCHEMBL27932294 0.76 CHRM1 (0.62) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL275821 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173704-A2 PROCESS FOR THE PREPARATION OF ETHYLGERANONITRILE BASF SE (DE) 2010-04-14 EP disclosed
WO-2009013199-A3 PROCESS FOR THE PREPARATION OF ETHYLGERANONITRILE BASF SE (DE) 2009-04-02 WO disclosed
WO-2009013199-A2 PROCESS FOR THE PREPARATION OF ETHYLGERANONITRILE BASF SE (DE) 2009-01-29 WO disclosed