Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327093 | 0.86 | RAB9A (0.40) | TSHRNPSR1RAB9ANISCHHDAC4 | |
| SCHEMBL10518091 | 0.85 | RAB9A (0.38) | TSHRNPSR1RAB9ASMN1; SMN2NISCH | |
| SCHEMBL6618609 | 0.83 | ATM (0.42) | TSHRRAB9ANISCHGAAHDAC4 | |
| SCHEMBL2720399 | 0.81 | RAB9A (0.57) | TSHRNPSR1RAB9ASMN1; SMN2GAA | |
| SCHEMBL31445349 | 0.81 | RAB9A (0.57) | TSHRNPSR1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL11349059 | 0.80 | RAB9A (0.56) | TSHRNPSR1RAB9ASMN1; SMN2GAA | |
| SCHEMBL28002393 | 0.80 | RAB9A (0.37) | TSHRNPSR1RAB9ANISCHHDAC4 | |
| SCHEMBL28440436 | 0.76 | FABP7 (0.39) | RAB9AF2KMT2A | |
| SCHEMBL14287323 | 0.75 | EDNRA (0.41) | TSHRNPSR1SMN1; SMN2NISCHEDNRA | |
| SCHEMBL1476722 | 0.75 | EDNRA (0.41) | TSHRNPSR1SMN1; SMN2NISCHEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473274-B2 | Heterocyclic compound as inhibitor of casein kinase 1-δ and/or activin receptor-like kinase 5 | ALCHEMEDICINE, INC. (JP) | 2025-11-18 | — | — | US | disclosed |
| WO-2024061340-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-03-28 | — | — | WO | disclosed |
| US-11898009-B2 | Polyimide, laminate, and electronic device including same | UBE CORPORATION (JP) | 2024-02-13 | — | — | US | disclosed |
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | ALCHEMEDICINE, INC. (JP) | 2023-06-15 | — | — | US | disclosed |
| EP-2922535-B1 | THROMBIN INHIBITORS | MERCK SHARP & DOHME (US) | 2021-11-10 | — | — | EP | disclosed |
| EP-2922535-B1 | THROMBIN INHIBITORS | MERCK SHARP & DOHME (US) | 2021-11-10 | — | — | EP | disclosed |
| US-20210171714-A1 | POLYIMIDE, LAYERED PRODUCT, AND ELECTRONC DEVICE INCLUDING SAME | UBE CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| WO-2020208884-A1 | FILM-FORMING COMPOSITION, CURED FILM, AND RETARDATION FILM | JSR株式会社 | 2020-10-15 | — | — | WO | disclosed |
| EP-3661931-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019027054-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-02-07 | — | — | WO | disclosed |
| US-20150315141-A1 | Thrombin Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-11-05 | — | — | US | disclosed |
| CN-104428914-A | Bulk heterojunction-type organic solar cell comprising imide-based conjugated backbone compound as photoactive material | TATA STEEL NEDERLAND TECHNOLOGY BV | 2015-03-18 | — | — | CN | disclosed |
| WO-2014109946-A1 | COMPOSITE POLYAMIDE MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-17 | — | — | WO | disclosed |
| EP-2170850-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2010-04-07 | — | — | EP | disclosed |
| CN-100564375-C | (3Z) -3- (2, 3-dihydro-1H-inden-1-ylidene) -1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN INC (US) | 2009-12-02 | — | — | CN | disclosed |
| WO-2008152149-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2008-12-18 | — | — | WO | disclosed |
| EP-1187822-A1 | PROCESS FOR THE PREPARATION OF 5-CARBOXPHTHALIDE AND ITS USE FOR THE PRODUCTION OF CITALOPRAM | Norpharma SpA (IT) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001053284-A1 | PROCESS FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE AND ITS USE FOR THE PRODUCTION OF CITALOPRAM | INFOSINT SA (CH) | 2001-07-26 | — | — | WO | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | CSNK1A1, CSNK1G1, CSNK1D | TSHR 1403/4885NPSR1 1455/4885RAB9A 4019/4885 |
| US-20150315141-A1 | Thrombin Inhibitors | F3, F2, F9 | TSHR 20/4885NPSR1 188/4885RAB9A 1296/4885 |
| US-12473274-B2 | Heterocyclic compound as inhibitor of casein kinase 1-δ and/or activin receptor-like kinase 5 | CSNK1A1, CSNK1G1, CKS1B | TSHR 1373/4885NPSR1 1431/4885RAB9A 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.