Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 12/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634957 | 0.82 | SSTR5 (0.42) | SSTR5WNK1HRH1HTR2BDRD2 | |
| SCHEMBL3639410 | 0.82 | SSTR5 (0.49) | SSTR5 | |
| SCHEMBL5007394 | 0.80 | SSTR5 (0.59) | SSTR5HRH1HTR2B | |
| SCHEMBL3634853 | 0.79 | SSTR5 (0.51) | SSTR5HRH1HTR2BSSTR1 | |
| SCHEMBL3631514 | 0.79 | SSTR5 (0.42) | SSTR5HRH1HTR2BSSTR1UTS2R | |
| SCHEMBL3639957 | 0.78 | SSTR5 (0.52) | SSTR5 | |
| SCHEMBL3635691 | 0.76 | SSTR5 (0.46) | SSTR5 | |
| SCHEMBL3725485 | 0.72 | SSTR5 (0.48) | SSTR5HRH1HTR2BSSTR1 | |
| SCHEMBL3639689 | 0.71 | SSTR5 (0.58) | SSTR5HRH1HTR2B | |
| SCHEMBL3637751 | 0.69 | SSTR5 (0.57) | SSTR5HRH1HTR2BSSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155718-A2 | ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF SOMATOSTATINE RECEPTOR ACTIVITY | F. Hoffmann-Roche AG (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008148710-A2 | ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF SOMATOSTATINS RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-11 | — | — | WO | disclosed |