SCHEMBL3640208

SCHEMBL3640208

CC(NC(=O)CC(=O)Nc1ccc(C(=N)N)cc1)c1cccc(-c2ccc(NS(C)(=O)=O)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F7 P08709 17/20 0.52
F2 P00734 9/20 0.52
F9 P00740 2/20 0.49
F10 P00742 3/20 0.48
F3 P13726 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860395 1.00 F7 (0.52) F7F2F9F10F3
Trifluoroacetic Acid SCHEMBL842198 0.94 F7 (0.47) F7F2F9F10F3
SCHEMBL860309 0.87 F7 (0.58) F7F2F10
SCHEMBL8097097 0.80 F7 (0.37) F7F2F9F10
SCHEMBL860369 0.78 F7 (0.53) F7F2F10
SCHEMBL841845 0.76 F7 (0.55) F7F2F10
SCHEMBL860287 0.76 F7 (0.52) F7F2F10
Trifluoroacetic Acid SCHEMBL842110 0.75 F2 (0.50) F7F2F10
SCHEMBL8104704 0.75 F7 (0.52) F7F2F10
SCHEMBL861199 0.74 F7 (0.61) F7F2F9F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2176223-A1 MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY Sanofi-Aventis (FR) 2010-04-21 EP disclosed
WO-2009007015-A1 MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY SANOFI-AVENTIS (FR) 2009-01-15 WO disclosed