Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 7/20 | 0.37 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860395 | 0.80 | F7 (0.52) | F7F2F10F9 | |
| SCHEMBL3640208 | 0.80 | F7 (0.52) | F7F2F10F9 | |
| Trifluoroacetic Acid SCHEMBL842198 | 0.75 | F7 (0.47) | F7F2F10F9 | |
| SCHEMBL13524607 | 0.67 | RXRA (0.53) | ROCK2ROCK1 | |
| SCHEMBL860309 | 0.67 | F7 (0.58) | F7F2F10 | |
| SCHEMBL842032 | 0.65 | HSD17B1 (0.50) | ROCK2ROCK1 | |
| SCHEMBL860476 | 0.65 | HSD17B1 (0.50) | ROCK2ROCK1 | |
| SCHEMBL15937527 | 0.63 | LIPG (0.69) | ROCK2PHGDH | |
| SCHEMBL15937528 | 0.63 | LIPG (0.69) | ROCK2PHGDH | |
| SCHEMBL860369 | 0.60 | F7 (0.53) | F7F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007015-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |