Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 11/20 | 0.36 |
| ▸ | UBE2M | P61081 | 5/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640188 | 0.82 | GHSR (1.00) | GHSRALDH1A1POLBTACR1KCNH2 | |
| Hydrochloric Acid SCHEMBL3740772 | 0.81 | GHSR (0.98) | GHSRALDH1A1POLBTACR1KCNH2 | |
| SCHEMBL3742458 | 0.79 | GHSR (0.68) | GHSRTACR1KCNH2 | |
| SCHEMBL3639639 | 0.79 | GHSR (0.68) | GHSRTACR1KCNH2 | |
| SCHEMBL3640251 | 0.78 | GHSR (0.75) | GHSRALDH1A1POLBTACR1CNR1 | |
| SCHEMBL3638174 | 0.78 | GHSR (0.78) | GHSRALDH1A1POLBTACR1 | |
| Hydrochloric Acid SCHEMBL3746485 | 0.77 | GHSR (0.77) | GHSRALDH1A1POLBTACR1 | |
| SCHEMBL13044464 | 0.77 | GHSR (0.75) | GHSRALDH1A1POLBTACR1 | |
| SCHEMBL3638374 | 0.73 | GHSR (0.48) | GHSRALDH1A1POLBTACR1UBE2M | |
| SCHEMBL3636450 | 0.72 | GHSR (0.68) | GHSRTACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | GHSR 2/4885ALDH1A1 2645/4885POLB 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.