Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13010141 | 1.00 | REN (0.74) | RENCYP3A4 | |
| SCHEMBL3635271 | 0.93 | REN (0.64) | RENCYP3A4 | |
| SCHEMBL13010186 | 0.92 | REN (0.74) | RENCYP3A4 | |
| SCHEMBL3781392 | 0.90 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL3781390 | 0.90 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL13320869 | 0.88 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL4750381 | 0.88 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL13250052 | 0.87 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL8164305 | 0.87 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL13010145 | 0.86 | REN (0.79) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167609-A1 | RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009096996-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-06 | — | — | WO | disclosed |