Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639860 | 0.98 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL3638696 | 0.94 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL4739907 | 0.92 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL2998136 | 0.91 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL3008467 | 0.91 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL3006442 | 0.89 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL3012084 | 0.89 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL3003390 | 0.89 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL3638516 | 0.89 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL3640876 | 0.89 | HCRTR1 (0.66) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155739-A1 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008139416-A1 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-11-20 | — | — | WO | disclosed |