⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115519 | 0.76 | — | — | |
| SCHEMBL7022900 | 0.72 | — | — | |
| SCHEMBL1805156 | 0.67 | — | — | |
| SCHEMBL6202456 | 0.67 | — | — | |
| SCHEMBL300230 | 0.67 | — | — | |
| SCHEMBL4300534 | 0.67 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL28038 | 0.67 | — | — | |
| SCHEMBL1162544 | 0.67 | — | — | |
| SCHEMBL1644673 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL732030 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645937-B | Aza spiro ring and polycyclic andrographolide compound, preparation method thereof, pharmaceutical composition and application thereof | 深圳湾实验室 | 2022-05-31 | — | — | CN | disclosed |
| CN-114315041-A | Process system for efficiently treating wastewater | 宁夏万博生物科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210244374-A1 | APPARATUS AND METHODS FOR X-RAY IMAGING | XENSELAB LLC | 2021-08-12 | — | — | US | disclosed |
| EP-3829441-A1 | SYSTEM AND METHODS FOR X-RAY IMAGING AND A CONTRAST AGENT | XENSELAB LLC (US) | 2021-06-09 | — | — | EP | disclosed |
| CN-112739264-A | System and method for X-ray imaging and contrast agent | 森瑟实验室有限责任公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112645937-A | Aza spiro ring and polycyclic andrographolide compound, preparation method thereof, pharmaceutical composition and application thereof | 深圳湾实验室 | 2021-04-13 | — | — | CN | disclosed |
| WO-2020028422-A9 | SYSTEM AND METHODS FOR X-RAY IMAGING AND A CONTRAST AGENT | XENSELAB LLC (US) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020028422-A1 | SYSTEM AND METHODS FOR X-RAY IMAGING AND A CONTRAST AGENT | XENSELAB LLC (US) | 2020-02-06 | — | — | WO | disclosed |
| EP-2439204-B1 | HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER | NISSAN CHEMICAL IND LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| EP-2765187-A1 | METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS | Nissan Chemical Industries, Ltd. (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-5662883-A | DISSOLVE IN BASE, ADD AQUEOUS SURFACE MODIFIER, NEUTRALIZE WITH ACID TO FORM DISPERSION | NANOSYSTEMS L.L.C. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1997021435-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |
| US-5560932-A | DISSOLVING PHARMACEUTICAL IN AQUEOUS BASE, ADDING AQUEOUS SOLUTION OF SURFACE MODIFIER, NEUTRALIZING ALKALINE SOLUTION WITH ACID TO FORM DISPERSION | NANO SYSTEMS L.L.C. (US) | 1996-10-01 | — | — | US | disclosed |
| WO-1996025182-A1 | PROCESS OF PREPARING X-RAY CONTRAST COMPOSITIONS CONTAINING NANOPARTICLES | NANOSYSTEMS L.L.C. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-5543133-A | PREPARING PREMIX OF CONTRAST AGENT AND SURFACTANT; REDUCTION OF PARTICLE SIZE | NANOSYSTEMS L.L.C. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5451393-A | X-ray contrast compositions useful in medical imaging | EASTMAN KODAK COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| US-5318767-A | X-ray contrast compositions useful in medical imaging | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5298499-A | S-2-(substituted ethylamino)ethyl phosphorothioates | RESEARCH TRIANGLE INSTITUTE (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0498482-A2 | X-ray contrast compositions useful in medical imaging | NanoSystems L.L.C. (US) | 1992-08-12 | — | — | EP | disclosed |
| US-4968809-A | Spirofluoreneisothiazolidinone dioxides as aldose reductase inhibitors | NESTLE S.A. A COMPANY OF SWITZERLAND (CH) | 1990-11-06 | — | — | US | disclosed |