Tioxolone

Tioxolone

SCHEMBL36433

O=c1oc2cc(O)ccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 1.00
MAOB P27338 7/20 1.00
HPGD P15428 3/20 1.00
MAPT P10636 2/20 1.00
HTT P42858 2/20 1.00
CA2 P00918 1/20 1.00
ALPI P09923 1/20 1.00
ALPG P10696 1/20 1.00
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
KMT2A Q03164 2/20 0.46
CA12 O43570 2/20 0.46
GLA P06280 2/20 0.46
GAA P10253 2/20 0.46
AKR1B1 P15121 2/20 0.46
CASP1 P29466 2/20 0.46
CASP7 P55210 2/20 0.46
MCL1 Q07820 2/20 0.46
CA9 Q16790 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tioxolone SCHEMBL29427713 1.00 MAOA (1.00) MAOAMAOBHPGDMAPTHTT
Tioxolone SCHEMBL13723132 0.98 MAOA (0.96) MAOAMAOBHPGDMAPTHTT
SCHEMBL2101251 0.84 MAPT (0.72) MAOAMAOBHPGDMAPTHTT
SCHEMBL30273047 0.84 MAPT (0.72) MAOAMAOBHPGDMAPTHTT
Mesulfen SCHEMBL28142835 0.82 MAOB (0.68) MAOAMAOBHPGDMAPTHTT
Tioxolone SCHEMBL6586457 0.79 MAOB (0.88) MAOAMAOBHPGDMAPTHTT
Bithionol SCHEMBL28086618 0.78 MAOA (0.61) MAOAMAOBHPGDMAPTHTT
SCHEMBL3438986 0.78 MAPT (0.63) MAOAMAOBHPGDMAPTHTT
SCHEMBL5541064 0.78 MAOA (0.63) MAOAMAOBHPGDMAPTHTT
SCHEMBL2056163 0.76 MAOA (0.61) MAOAMAOBHPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4204 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122088605-A Hierarchical reinforcement learning method, device, computer equipment and medium based on stream matching 2026-05-26 CN claimed
CN-122093738-A Semi-blind direct positioning method for thermal noise communication system 2026-05-26 CN claimed
CN-122092921-A Anti-unmanned aerial vehicle-oriented general sense integrated multi-unmanned aerial vehicle beam track design method 2026-05-26 CN claimed
CN-120128933-B Federal learning method, device and equipment for multi-base-station unmanned vehicle UNIT 63891 OF PLA (CN) 2026-05-26 CN claimed
CN-122088573-A Channel mixing precision quantification method and system after training of neural network 2026-05-26 CN claimed
CN-121615150-B Automatic penetration test method and system based on cognition decision model 华中科技大学 2026-05-19 CN claimed
CN-122066949-A Steel tube concrete arch bridge arch rib point cloud segmentation method based on iterative geometric fitting and neighborhood consistency constraint 重庆交通大学 2026-05-19 CN claimed
CN-120975561-B Risk assessment and regulation method and device for multi-energy cooperative heating system 中铁第一勘察设计院集团有限公司 2026-05-15 CN claimed
CN-116222559-B Strapdown inertial navigation pedestrian three-dimensional position correction method 重庆邮电大学 2026-05-12 CN claimed
CN-115134913-B Ultra-wideband positioning and orientation tag based on geometric constraint and method thereof 长春理工大学 2026-05-12 CN claimed
EP-1062223-A1 COMPOSITION CONTAINING A PRECURSOR CAPABLE OF BEING HYDROLYSED BY GLUCOCEREBROSIDASE Pierre Fabre Dermo-Cosmetique (FR) 2000-12-27 EP claimed
EP-1035828-A2 TOPICAL COMPOSITIONS FOR REGULATING THE OILY/SHINY APPEARANCE OF SKIN THE PROCTER & GAMBLE COMPANY (US) 2000-09-20 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1999046273-A1 COMPOSITION CONTAINING A PRECURSOR CAPABLE OF BEING HYDROLYSED BY GLUCOCEREBROSIDASE PIERRE FABRE DERMO-COSMETIQUE (FR) 1999-09-16 WO claimed
WO-1999018919-A2 TOPICAL COMPOSITIONS FOR REGULATING THE OILY/SHINY APPEARANCE OF SKIN THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO claimed
EP-0304649-B1 Salts of 6-piperidino-2,4-diaminopyrimidin-3-oxide and of derivatives of thiamorpholin-3-on-5-carboxylic acid, their cosmetical and medicinal use. L'OREAL (FR) 1991-03-20 EP claimed
US-4970063-A WATER SOLUBLE MINOXIDIL SALT L'OREAL (FR) 1990-11-13 US claimed
EP-0304649-A1 Salts of 6-piperidino-2,4-diaminopyrimidin-3-oxide and of derivatives of thiamorpholin-3-on-5-carboxylic acid, their cosmetical and medicinal use. L'OREAL (FR) 1989-03-01 EP claimed
US-4626529-A AMINE-NEUTRALIZED ANIONIC SURFACTANT L'OREAL (FR) 1986-12-02 US claimed
US-4289183-A Noiseless lug tires BRIDGESTONE TIRE COMPANY LIMITED (JP) 1981-09-15 US claimed