SCHEMBL364348

SCHEMBL364348

C[Si](C)(C)C#CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3286850 0.72
SCHEMBL9284610 0.72
SCHEMBL7144993 0.67 APLNR (0.36)
SCHEMBL3784264 0.67
SCHEMBL3019375 0.67
SCHEMBL1163814 0.65
SCHEMBL821860 0.64
SCHEMBL3002264 0.63
SCHEMBL9094601 0.63
SCHEMBL9098453 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209521-A Preparation method of propynyl chloride 台州道致科技股份有限公司 2023-12-12 CN claimed
CN-115557984-A Synthetic method of 3-trimethylsilyl propiolic aldehyde 上海易恩化学技术有限公司 2023-01-03 CN claimed
CN-111825679-B Novel spiro-pyrrole [2, 1-b ] quinazolinone derivative and preparation method and application thereof 广西师范大学 2022-04-12 CN claimed
CN-112480131-B Porphyrin compound, preparation method thereof and application thereof in secondary battery anode material 湘潭大学 2022-01-04 CN claimed
CN-112480131-A Porphyrin compound, preparation method thereof and application thereof in secondary battery anode material 湘潭大学 2021-03-12 CN claimed
CN-111825679-A Novel spiro-pyrrole [2, 1-b ] quinazolinone derivative and preparation method and application thereof 广西师范大学 2020-10-27 CN claimed
CN-109135493-A A kind of useless paint processing method of furniture paint spraying 温州职业技术学院 2019-01-04 CN claimed
CN-1119321-C Asymetric synthesis of chiral beta-amino acids SEARLE & CO (US) 2003-08-27 CN claimed
EP-0912495-B1 ASYMETRIC SYNTHESIS OF CHIRAL BETA-AMINO ACIDS SEARLE & CO (US) 2001-11-21 EP claimed
EP-0839128-B1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE SEARLE & CO (US) 2000-04-05 EP claimed
CN-1225084-A Asymetric synthesis of chiral beta-amino acids SEARLE & CO (US) 1999-08-04 CN claimed
EP-0912495-A1 ASYMETRIC SYNTHESIS OF CHIRAL BETA-AMINO ACIDS G.D. SEARLE &amp; CO. (US) 1999-05-06 EP claimed
US-5840961-A Asymmetric synthesis of chiral beta-amiNo acids G. D. SEARLE & CO. (US) 1998-11-24 US claimed
EP-0839128-A1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE G.D. SEARLE &amp; CO. (US) 1998-05-06 EP claimed
WO-1998002410-A1 ASYMETRIC SYNTHESIS OF CHIRAL BETA-AMINO ACIDS G.D. SEARLE & CO. (US) 1998-01-22 WO claimed
US-5631399-A MULTISTAGE SYNTHESIS USING TRIMETHYLSILYLACETYLENE WITH BUTYLLITHIUM AND FORMYLMORPHOLINE, THEN ACID HYDROLYSIS G. D. SEARLE & CO. (US) 1997-05-20 US claimed
WO-1997003947-A1 PROCESS FOR THE PREPARATION OF ETHYL 3S-[[4-[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]-1,4-DIOXOBUTYL]AMINO]-4-PENTYNOATE G.D. SEARLE & CO. (US) 1997-02-06 WO claimed
US-5536869-A Process for the preparation of ethyl 3S-[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-4-pentynoate G. D. SEARLE & CO. (US) 1996-07-16 US claimed
JP-9100285-A None JP disclosed
JP-H00967382-A 0001-01-01 JP disclosed