Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942071 | 0.93 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 | |
| SCHEMBL2001451 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 | |
| SCHEMBL22658080 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 | |
| SCHEMBL1645785 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 | |
| SCHEMBL4940887 | 0.85 | SOAT1 (0.41) | ALDH1A1MAPTL3MBTL1LMNAHSD17B10 | |
| SCHEMBL1085238 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP2D6MAPTL3MBTL1LMNA | |
| SCHEMBL4481930 | 0.75 | TP53 (0.37) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL3645141 | 0.74 | MAPT (0.35) | ALDH1A1MAPTHPGDLMNA | |
| Hydrochloric Acid SCHEMBL22683491 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 | |
| SCHEMBL13437369 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173749-A1 | 2-OXO-2- (2-PHENYL-5,6,7,8-TETRAHYDRO-INDOLIZIN-3-YL) -ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008145963-A1 | 2-OXO-2- (2-PHENYL-5,6,7,8-TETRAHYDRO-INDOLIZIN-3-YL) -ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2008-12-04 | — | — | WO | disclosed |