Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25312104 | 1.00 | USP2 (0.42) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL3646782 | 0.86 | LMNA (0.33) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL27944594 | 0.81 | LMNA (0.40) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL3959086 | 0.81 | LMNA (0.40) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL4655170 | 0.81 | LMNA (0.40) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL29159266 | 0.80 | USP2 (0.48) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL18825609 | 0.80 | USP2 (0.48) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL9763747 | 0.80 | USP2 (0.48) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL6247036 | 0.79 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL2871735 | 0.79 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4365189-B1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | HOFFMANN LA ROCHE (CH) | 2025-02-19 | — | — | EP | claimed |
| US-12098211-B2 | Prevention of disulfide bond reduction during recombinant production of polypeptides | GENENTECH, INC. (US) | 2024-09-24 | — | — | US | claimed |
| US-11987638-B1 | Prevention of disulfide bond reduction during recombinant production of polypeptides | GENENTECH, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-20240158527-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2024-05-16 | — | — | US | claimed |
| EP-4365189-A2 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2024-05-08 | — | — | EP | claimed |
| EP-4335863-A2 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | Genentech, Inc. (US) | 2024-03-13 | — | — | EP | claimed |
| EP-4245766-A9 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | Genentech, Inc. (US) | 2024-01-24 | — | — | EP | claimed |
| US-20230383004-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2023-11-30 | — | — | US | claimed |
| EP-4245766-A2 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | Genentech, Inc. (US) | 2023-09-20 | — | — | EP | claimed |
| US-11639395-B2 | Prevention of disulfide bond reduction during recombinant production of polypeptides | GENENTECH, INC. (US) | 2023-05-02 | — | — | US | claimed |
| US-20210188993-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2021-06-24 | — | — | US | claimed |
| WO-2020028616-A1 | METHODS FOR MANUFACTURING RECOMBINANT PROTEIN COMPRISING A DISULFIDE BOND | LONZA LTD (CH) | 2020-02-06 | — | — | WO | claimed |
| EP-3327026-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | Genentech, Inc. (US) | 2018-05-30 | — | — | EP | claimed |
| EP-2188302-B1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH INC (US) | 2017-11-01 | — | — | EP | claimed |
| US-20140128575-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2014-05-08 | — | — | US | claimed |
| EP-2586788-A1 | Prevention of disulfide bond reduction during recombinant production of polypeptides | Genentech, Inc. (US) | 2013-05-01 | — | — | EP | claimed |
| US-20130017598-A1 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2013-01-17 | — | — | US | claimed |
| EP-2188302-A2 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | Genentech, Inc. (US) | 2010-05-26 | — | — | EP | claimed |
| US-20090053786-A1 | Prevention of disulfide bond reduction during recombinant production of polypeptides | GENENTECH, INC. | 2009-02-26 | — | — | US | claimed |
| WO-2009009523-A2 | PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES | GENENTECH, INC. (US) | 2009-01-15 | — | — | WO | claimed |