Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645445 | 1.00 | MAPK1 (0.42) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3643787 | 0.91 | MAPK1 (0.48) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3643788 | 0.91 | MAPK1 (0.48) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3643188 | 0.85 | MAPK1 (0.44) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3643190 | 0.85 | MAPK1 (0.44) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL2993836 | 0.84 | MAPK1 (0.50) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL2993832 | 0.84 | MAPK1 (0.50) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3002939 | 0.82 | MAPK1 (0.50) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3002941 | 0.82 | MAPK1 (0.50) | MAPK1IKBKBRAF1RPS6KB1AKT1 | |
| SCHEMBL3636699 | 0.78 | MAPK1 (0.48) | MAPK1IKBKBRAF1RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178835-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009004650-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-01-08 | — | — | WO | disclosed |