Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.48 |
| ▸ | IKBKB | O14920 | 5/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.48 |
| ▸ | RAF1 | P04049 | 3/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.48 |
| ▸ | AKT1 | P31749 | 3/20 | 0.48 |
| ▸ | AKT2 | P31751 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | XBP1 | P17861 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636696 | 1.00 | MAPK1 (0.48) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL2997382 | 0.91 | IKBKB (0.44) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL2997384 | 0.91 | IKBKB (0.44) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL3000161 | 0.84 | IKBKB (0.44) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL3000164 | 0.84 | IKBKB (0.44) | MAPK1IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL3006044 | 0.83 | ACHE (0.53) | MAPK1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3006047 | 0.83 | ACHE (0.53) | MAPK1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3004044 | 0.82 | PIM1 (0.42) | MAPK1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3004040 | 0.82 | PIM1 (0.42) | MAPK1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3004973 | 0.81 | PIM1 (0.41) | MAPK1MAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178835-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009004650-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-01-08 | — | — | WO | disclosed |