Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | PRKDC | P78527 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123899 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL211200 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL11670410 | 0.85 | MAPT (0.62) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL9838976 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL28054126 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL210330 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL29800558 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL7631563 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL10478006 | 0.82 | MAPT (0.68) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL7631569 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | claimed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | claimed |
| US-8480662-B2 | Systems and devices for photoablation | CARDIAC PACEMAKERS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2188014-A1 | SYSTEMS AND DEVICES FOR PHOTOABLATION | Cardiac Pacemakers, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009025826-A1 | SYSTEMS AND DEVICES FOR PHOTOABLATION | CARDIAC PACEMAKERS, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| US-20090054883-A1 | Systems and devices for photoablation | CARDIAC PACEMAKERS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | disclosed |