Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377345 | 0.92 | MALT1 (0.49) | AKT1SMOMALT1 | |
| SCHEMBL3946323 | 0.79 | AKT1 (0.49) | AKT1SMPD3 | |
| SCHEMBL13148708 | 0.78 | CA12 (0.59) | AKT1MTNR1AMTNR1BSMPD3SMO | |
| SCHEMBL4436052 | 0.78 | PDE10A (0.58) | — | |
| SCHEMBL2270852 | 0.77 | SMPD3 (0.48) | AKT1MTNR1AMTNR1BCNR2OPRK1 | |
| SCHEMBL3216221 | 0.76 | CKS1B (0.53) | CNR2OPRK1OPRM1OPRD1OGFRL1 | |
| SCHEMBL17628004 | 0.76 | CNR2 (0.53) | AKT1CNR2OPRK1ACKR3SMPD3 | |
| SCHEMBL17628001 | 0.76 | CNR2 (0.53) | AKT1CNR2OPRK1ACKR3SMPD3 | |
| SCHEMBL27517766 | 0.76 | GRIN2D (0.49) | MALT1HSD11B1 | |
| SCHEMBL2412747 | 0.75 | AKT1 (0.46) | AKT1MTNR1AMTNR1BCNR2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182914-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'Oreal (FR) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009019383-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL (FR) | 2009-02-12 | — | — | WO | disclosed |