Acetic Acid

Acetic Acid

SCHEMBL3645976

CC(=O)O.CCCCCCCCS(=O)(=O)[O-].[Na+]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.41
EPHX2 P34913 2/20 0.55
FAAH O00519 5/20 0.45
TSHR P16473 4/20 0.44
RECQL P46063 2/20 0.44
GLA P06280 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
BLM P54132 1/20 0.44
CES2 O00748 5/20 0.43
CES1 P23141 4/20 0.43
PPARG P37231 4/20 0.41
PPARD Q03181 4/20 0.41
PPARA Q07869 4/20 0.41
GPR84 Q9NQS5 3/20 0.41
HDAC11 Q96DB2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28730807 0.98 EPHX2 (0.54) EPHX2FAAHTSHRRECQLGLA
Acetic Acid SCHEMBL29141866 0.94 EPHX2 (0.50) EPHX2FAAHTSHRRECQLGLA
Bicarbonate SCHEMBL28494347 0.92 EPHX2 (0.55) EPHX2FAAHTSHRRECQLGLA
Acetic Acid SCHEMBL28201981 0.92 EPHX2 (0.55) EPHX2FAAHTSHRRECQLGLA
Bicarbonate SCHEMBL5377762 0.92 EPHX2 (0.55) EPHX2FAAHTSHRRECQLGLA
Acetic Acid SCHEMBL27751674 0.90 EPHX2 (0.54) EPHX2FAAHTSHRRECQLGLA
Methyl Alcohol SCHEMBL25250336 0.89 EPHX2 (0.56) EPHX2FAAHTSHRRECQLGLA
Methyl Alcohol SCHEMBL284907 0.89 EPHX2 (0.56) EPHX2FAAHTSHRRECQLGLA
Methyl Alcohol SCHEMBL10778854 0.89 EPHX2 (0.56) EPHX2FAAHTSHRRECQLGLA
Methyl Alcohol SCHEMBL135872 0.89 EPHX2 (0.56) EPHX2FAAHTSHRRECQLGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2166838-B1 TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME CHX TECH INC (CA) 2018-10-24 EP disclosed
EP-2166838-A2 TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME CHX Technologies Inc. (CA) 2010-03-31 EP disclosed
WO-2008156559-A2 TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME CHX TECHNOLOGIES, INC. (CA) 2008-12-24 WO disclosed