⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49447 | 0.75 | — | — | |
| SCHEMBL1840414 | 0.72 | — | — | |
| SCHEMBL175234 | 0.72 | TDP1 (0.46) | — | |
| SCHEMBL1416651 | 0.71 | — | — | |
| Formaldehyde SCHEMBL9721282 | 0.71 | — | — | |
| SCHEMBL9428824 | 0.69 | — | — | |
| SCHEMBL1479352 | 0.69 | — | — | |
| SCHEMBL4409980 | 0.69 | — | — | |
| SCHEMBL7072383 | 0.69 | — | — | |
| SCHEMBL6353648 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 966 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | claimed |
| WO-2023060369-A1 | NOVEL CARBIMIDATE SUBSTITUTED BICYCLIC COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-04-20 | — | — | WO | claimed |
| US-11186583-B2 | 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidines for treatment of lymphoma | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-11-30 | — | — | US | claimed |
| EP-3749670-B1 | 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA | UNIV PALACKEHO (CZ) | 2021-10-06 | — | — | EP | claimed |
| EP-3749670-A1 | 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA | Univerzita Palackeho v Olomouci (CZ) | 2020-12-16 | — | — | EP | claimed |
| US-20200361943-A1 | 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-11-19 | — | — | US | claimed |
| US-10597477-B2 | Finely divided aqueous emulsion polymers and use thereof for hydrophobic coatings | BASF SE (DE) | 2020-03-24 | — | — | US | claimed |
| EP-3194454-B1 | FINELY DIVIDED AQUEOUS EMULSION POLYMERS AND USE THEREOF FOR HYDROPHOBIC COATINGS | BASF SE (DE) | 2019-11-06 | — | — | EP | claimed |
| WO-2019149295-A1 | 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2019-08-08 | — | — | WO | claimed |
| CN-109021033-A | A kind of chitosan oligosaccharide derivative and preparation method thereof containing thiocarbamide and diethoxy phosphinylidyne amine structure | 中国科学院海洋研究所 | 2018-12-18 | — | — | CN | claimed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | claimed |
| EP-0225182-A2 | Cephalosporin compounds | ICI PHARMA (FR) | 1987-06-10 | — | — | EP | claimed |
| EP-0182633-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-05-28 | — | — | EP | claimed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| US-4311478-A | HAIR DYES | L'OREAL (FR) | 1982-01-19 | — | — | US | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4035420-A | CARDIOVASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1977-07-12 | — | — | US | claimed |