SCHEMBL49447

SCHEMBL49447

[CH2]CCNC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28833081 0.88 TDP1 (0.32)
SCHEMBL1416651 0.83
SCHEMBL9428824 0.81
SCHEMBL175234 0.81 TDP1 (0.46)
SCHEMBL1415925 0.79 KDM4E (0.42)
SCHEMBL27689733 0.78
SCHEMBL11648481 0.76 TSHR (0.46)
SCHEMBL36468 0.75
SCHEMBL1837224 0.75 KDM4E (0.48)
SCHEMBL1309431 0.75 TDP1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325101-A Amphoteric silicon-based sheet material and preparation method and application thereof 华南理工大学 2024-07-12 CN claimed
US-20240218022-A1 ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-04 US claimed
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN THERAPEUTICS, INC. (US) 2024-06-20 US claimed
WO-2024059472-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-03-21 WO claimed
EP-4313095-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-Gen Therapeutics, Inc. (US) 2024-02-07 EP claimed
CN-112812361-B Preparation method of silicon dioxide powder filler, powder filler obtained by preparation method and application of powder filler 浙江三时纪新材科技有限公司 2024-01-09 CN claimed
CN-117326588-A Preparation method of nano zirconia powder and dispersion liquid and brightness enhancement film 东莞市光志光电有限公司 2024-01-02 CN claimed
WO-2023225661-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-23 WO claimed
CN-117098544-A Diterpenoid compounds acting on Protein Kinase C (PKC) K-GEN治疗股份有限公司 2023-11-21 CN claimed
CN-117089076-A Multifunctional hyperbranched polysiloxane, resin modified by multifunctional hyperbranched polysiloxane for anti-corrosion and anti-fouling coating and preparation method of resin 北京航空航天大学 2023-11-21 CN claimed
EP-0055562-B1 CEPHALOSPORIN DERIVATIVES ICI PHARMA (FR) 1986-02-12 EP claimed
US-4492692-A BACTERICIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-08 US claimed
US-4482656-A Method for manufacturing a composition for coating substrates with an abrasion-resistant transparent and translucent film BATTELLE DEVELOPMENT CORPORATION (US) 1984-11-13 US claimed
EP-0055099-B1 PENICILLIN DERIVATIVES ICI PHARMA (FR) 1984-10-24 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0072608-A2 Process for the preparation of cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-02-23 EP claimed
EP-0071370-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them ICI PHARMA (FR) 1983-02-09 EP claimed
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP claimed
EP-0055099-A1 Penicillin derivatives ICI PHARMA (FR) 1982-06-30 EP claimed
US-4035420-A CARDIOVASCULAR DISORDERS AKTIEBOLAGET HASSLE (SW) 1977-07-12 US claimed