Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424990 | 0.92 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL1424407 | 0.90 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL3287325 | 0.86 | DGAT1 (0.83) | DGAT1 | |
| Pf-04620110 SCHEMBL1424359 | 0.77 | DGAT1 (1.00) | DGAT1 | |
| Pf-04620110 SCHEMBL1425038 | 0.77 | DGAT1 (1.00) | DGAT1 | |
| Pf-04620110 SCHEMBL1424362 | 0.77 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL3289248 | 0.77 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL3289255 | 0.77 | DGAT1 (0.75) | DGAT1 | |
| SCHEMBL12810904 | 0.76 | DGAT1 (0.84) | DGAT1 | |
| SCHEMBL1424394 | 0.75 | DGAT1 (0.75) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185567-A2 | SUBSTITUTED BICYCLOLACTAM COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016462-A2 | SUBSTITUTED BICYCLOLACTAM COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-05 | — | — | WO | disclosed |