Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017905 | 0.80 | CHRM3 (0.61) | CHRM3PRMT5 | |
| SCHEMBL1020291 | 0.79 | CHRM3 (0.61) | CHRM3PRMT5 | |
| SCHEMBL1020290 | 0.79 | CHRM3 (0.61) | CHRM3PRMT5 | |
| Hydrochloric Acid SCHEMBL1018725 | 0.79 | CHRM3 (0.60) | CHRM3 | |
| SCHEMBL7037977 | 0.79 | CHRM3 (0.69) | CHRM3 | |
| SCHEMBL1512308 | 0.78 | CHRM3 (0.72) | CHRM3SMN1; SMN2 | |
| SCHEMBL1019239 | 0.78 | KMT2A (0.58) | CHRM3 | |
| SCHEMBL12725260 | 0.77 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL3645530 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2 | |
| SCHEMBL28744419 | 0.77 | CYP2D6 (0.73) | CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190827-A1 | N-BENZYL, N' -ARYLCARBONYLPIPERAZINE DERIVATIVES AS LXR MODULATORS | N.V. Organon (NL) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009024550-A1 | N-BENZYL, N' -ARYLCARBONYLPIPERAZINE DERIVATIVES AS LXR MODULATORS | N.V. ORGANON (NL) | 2009-02-26 | — | — | WO | disclosed |