Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365756 | 0.83 | PDE10A (0.48) | TAAR1CASP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL9770077 | 0.83 | PDE10A (0.48) | TAAR1CASP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL792457 | 0.83 | ALDH1A1 (0.52) | TAAR1CASP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL30084985 | 0.83 | TAAR1 (0.69) | TAAR1CASP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL12401813 | 0.81 | ALDH1A1 (0.50) | TAAR1CASP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL698983 | 0.78 | TAAR1 (0.63) | TAAR1TSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL38658478 | 0.78 | TAAR1 (0.63) | TAAR1TSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL33767 | 0.78 | PRKCI (0.38) | CASP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL29378444 | 0.78 | PRKCI (0.38) | CASP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2232910 | 0.78 | ALDH1A1 (0.56) | TAAR1CASP1TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114615967-B | Two-component oxidation dyeing composition | 花王株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-116322619-A | Hair dyeing composition with improved durability | 花王株式会社 | 2023-06-23 | — | — | CN | disclosed |
| CN-116249511-A | Hair dyeing composition comprising blue dye | 花王株式会社 | 2023-06-09 | — | — | CN | disclosed |
| CN-111212627-B | Powder composition comprising a hair substantive dye | 花王株式会社 | 2023-02-17 | — | — | CN | disclosed |
| CN-114957156-A | Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114615967-A | Two-component oxidation dyeing composition | 花王株式会社 | 2022-06-10 | — | — | CN | disclosed |
| CN-111212627-A | Powder composition comprising a hair substantive dye | 花王株式会社 | 2020-05-29 | — | — | CN | disclosed |
| EP-2074986-B1 | Process for treating hair fibres using polysiloxane/polyurea | OREAL (FR) | 2013-05-15 | — | — | EP | disclosed |
| US-8293757-B2 | 5-(4-(haloalkoxy)phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors | IRM LLC (BM) | 2012-10-23 | — | — | US | disclosed |
| US-8293757-B2 | 5-(4-(haloalkoxy)phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors | IRM LLC (BM) | 2012-10-23 | — | — | US | disclosed |
| US-8293757-B2 | 5-(4-(haloalkoxy)phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors | IRM LLC (BM) | 2012-10-23 | — | — | US | disclosed |
| CN-101784530-A | 5- (4- (haloalkoxy) phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors | IRM LLC | 2010-07-21 | — | — | CN | disclosed |
| EP-2190825-A1 | 5- (4- (HALOALKOXY) PHENYL) PYRIMIDINE-2-AMINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-06-02 | — | — | EP | disclosed |
| EP-2074986-A1 | Process for treating hair fibres using polysiloxane/polyurea | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009026276-A1 | 5- (4- (HALOALKOXY) PHENYL) PYRIMIDINE-2-AMINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026276-A1 | 5- (4- (HALOALKOXY) PHENYL) PYRIMIDINE-2-AMINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-02-26 | — | — | WO | disclosed |
| EP-1935404-A1 | Composition for dyeing keratinous fibres comprising a polysiloxane-polyurea block copolymer | L'Oréal (FR) | 2008-06-25 | — | — | EP | disclosed |
| EP-1844816-A2 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'Oréal (FR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2004047780-A1 | METHOD AND KIT FOR THE GRADUAL PERMANENT COLORING OF HAIR | UNILEVER PLC (GB) | 2004-06-10 | — | — | WO | disclosed |