Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363756 | 1.00 | MEN1 (0.32) | MEN1KMT2AMAPTSMN1; SMN2OPRK1 | |
| SCHEMBL363413 | 0.90 | POLB (0.30) | — | |
| SCHEMBL363100 | 0.90 | POLB (0.30) | — | |
| SCHEMBL362836 | 0.90 | POLB (0.30) | — | |
| SCHEMBL363109 | 0.90 | CASR (0.34) | SMN1; SMN2PROKR1 | |
| SCHEMBL364569 | 0.86 | MAPT (0.36) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL365288 | 0.86 | CCR9 (0.34) | — | |
| SCHEMBL363868 | 0.86 | CCR9 (0.34) | — | |
| SCHEMBL364634 | 0.86 | PROKR1 (0.35) | MEN1KMT2AMAPTSMN1; SMN2PROKR1 | |
| SCHEMBL364263 | 0.85 | GPBAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |