Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363805 | 1.00 | GPBAR1 (0.31) | GPBAR1 | |
| SCHEMBL364180 | 0.91 | GPBAR1 (0.35) | GPBAR1 | |
| SCHEMBL364836 | 0.89 | POLB (0.32) | GPBAR1 | |
| SCHEMBL364539 | 0.89 | POLB (0.32) | GPBAR1 | |
| SCHEMBL364217 | 0.87 | GPBAR1 (0.30) | GPBAR1 | |
| SCHEMBL362932 | 0.85 | RAB9A (0.33) | GPBAR1 | |
| SCHEMBL363246 | 0.85 | NR1H2 (0.33) | GPBAR1 | |
| SCHEMBL363912 | 0.85 | WNT3A (0.35) | GPBAR1 | |
| SCHEMBL362081 | 0.85 | HSD17B1 (0.33) | — | |
| SCHEMBL363756 | 0.85 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |