Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657104 | 0.89 | SCN9A (0.35) | ENPP2SCN9ASCN5ANPY5RSMYD3 | |
| SCHEMBL1092716 | 0.87 | GPR119 (0.40) | ENPP2SCN9AGPR119 | |
| SCHEMBL1103978 | 0.83 | GPR119 (0.46) | SCN9AGPR119ALOX5APFEN1 | |
| SCHEMBL3654689 | 0.83 | ALOX5AP (0.41) | SCN9ASCN5ANPY5RGPR119ALOX5AP | |
| SCHEMBL1092418 | 0.81 | GPR119 (0.41) | ENPP2GPR119 | |
| SCHEMBL1092467 | 0.76 | GPR119 (0.40) | GPR119 | |
| SCHEMBL1103979 | 0.72 | GPR119 (0.48) | SCN9AGPR119ALOX5APFEN1 | |
| SCHEMBL1092380 | 0.71 | GPR119 (0.43) | GPR119ALOX5APFEN1 | |
| SCHEMBL1092504 | 0.70 | ALOX5AP (0.42) | SCN5ANPY5RGPR119ALOX5APFEN1 | |
| SCHEMBL1093473 | 0.69 | GPR119 (0.42) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197873-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-06-23 | — | — | EP | claimed |
| WO-2009038974-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-03-26 | — | — | WO | claimed |