SCHEMBL3650896

SCHEMBL3650896

C#CCCCCCCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.35
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4061244 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL7588597 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL5356889 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL8906942 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL4053845 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL3207889 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL23727498 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL8906883 1.00 DUT (0.35) DUTCYP1A2CYP2D6MAPTCYP2C9
SCHEMBL662237 0.98 DUT (0.36) DUT
SCHEMBL1578618 0.94 DUT (0.37) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611727-A1 ANTI-EVAPORATIVE LIPID FORMULATIONS University of Helsinki (FI) 2025-09-10 EP disclosed
WO-2024094759-A1 ANTI-EVAPORATIVE LIPID FORMULATIONS UNIVERSITY OF HELSINKI (FI) 2024-05-10 WO disclosed
EP-4329730-A2 A SPECIFIC COMBINATION OF LIPIDS AND METHODS AND USES RELATED THERETO Helsingin Yliopisto (FI) 2024-03-06 EP disclosed
US-20230024096-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER C4 THERAPEUTICS, INC. 2023-01-26 US disclosed
WO-2022229441-A2 A SPECIFIC COMBINATION OF LIPIDS AND METHODS AND USES RELATED THERETO HELSINGIN YLIOPISTO (FI) 2022-11-03 WO disclosed
EP-4051674-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2022-09-07 EP disclosed
WO-2021083949-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2021-05-06 WO disclosed
EP-2183267-B1 PROCESS FOR PREPARING 7-ALPHA-[9-(4,4,5,5,5-PENTAFLUOROTHIOPENTYL) NONYL]ESTRA-1,3,5(10)-TRIENE-3,17-BETA-DIOL IND CHIMICA SRL (IT) 2014-08-20 EP disclosed
EP-2183267-A2 PROCESS FOR PREPARING 7-ALPHA-[9-(4,4,5,5,5-PENTAFLUOROTHIOPENTYL) NONYL]ESTRA-1,3,5(10)-TRIENE-3,17-BETA-DIOL INDUSTRIALE CHIMICA S.r.l. (IT) 2010-05-12 EP disclosed
WO-2009013310-A2 PROCESS FOR PREPARING 7-ALPHA-[9-(4,4,5,5,5-PENTAFLUOROTHIOPENTYL)NONYL]ESTRA-1,3,5(10)-TRIENE-3,17-BETA-DIOL INDUSTRIALE CHIMICA S.R.L. (IT) 2009-01-29 WO disclosed
EP-0944613-B1 BENZOPYRAN DERIVATIVES CHUGAI PHARMACEUTICAL CO LTD (JP) 2002-10-09 EP disclosed
US-6153768-A RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS C & C RESEARCH LABORATORIES (KR) 2000-11-28 US disclosed
EP-0944613-A1 NOVEL BENZOPYRAN DERIVATIVES C & C Research Laboratories (KR) 1999-09-29 EP disclosed
WO-1998025916-A1 NOVEL BENZOPYRAN DERIVATIVES C & C RESEARCH LABORATORIES (KR) 1998-06-18 WO disclosed
EP-0163416-B1 PHENOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP disclosed
EP-0160508-B1 PHENOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP disclosed
US-4760061-A Antioestrogenic agent IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-26 US disclosed
US-4751240-A ANTIFERTILITY AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-06-14 US disclosed
EP-0163416-A2 Phenol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-04 EP disclosed
EP-0160508-A2 Phenol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024096-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER SMARCC1, SMARCC2, SMARCA2 DUT 1026/4885CYP1A2 3404/4885CYP2D6 4266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.