SCHEMBL3652197

SCHEMBL3652197

CCCCCCCCCCC[SiH2]O[SiH2]O[SiH3]

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2761420 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL30183845 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1332011 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1330675 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL1000117 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL11615190 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL540500 0.98 TSHR (0.33) TSHRTHRB
SCHEMBL15260490 0.98 TSHR (0.30) TSHRTHRB
SCHEMBL21522634 0.96 TSHR (0.32) TSHRTHRB
SCHEMBL21382204 0.96 TSHR (0.32) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2197887-A1 ORGANOSILOXANES CONTAINING ESTER DERIVATIVES OF ASCORBIC ACID Dow Corning Corporation (US) 2010-06-23 EP disclosed
WO-2009045709-A1 ORGANOSILOXANES CONTAINING ESTER DERIVATIVES OF ASCORBIC ACID DOW CORNING CORPORATION (US) 2009-04-09 WO disclosed