SCHEMBL540500

SCHEMBL540500

CCCCCCCCCC[SiH2]O[SiH2]O[SiH3].[Zn]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1000117 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL1332011 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL2761420 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL3652197 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL30183845 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL11615190 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL1330675 0.98 TSHR (0.35) TSHRTHRB
SCHEMBL15260490 0.96 TSHR (0.30) TSHRTHRB
SCHEMBL4635209 0.94 TSHR (0.32) TSHRTHRB
SCHEMBL21175550 0.94 TSHR (0.32) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104853732-B Water-in-oil type emulsified composition 株式会社资生堂 2017-09-22 CN claimed
CN-104853732-A Water-in-oil type emulsified composition SHISEIDO CO LTD 2015-08-19 CN claimed
CN-110769802-B Solid powder cosmetic 株式会社资生堂 2023-11-07 CN disclosed
US-10703913-B2 Titanium dioxide powder and cosmetic formulated therewith SHISEIDO COMPANY, LTD. (JP) 2020-07-07 US disclosed
CN-110769802-A Solid powder cosmetic 株式会社资生堂 2020-02-07 CN disclosed
US-20180371257-A1 TITANIUM DIOXIDE POWDER AND COSMETIC FORMULATED THEREWITH SHISEIDO COMPANY, LTD. (JP) 2018-12-27 US disclosed
EP-3395764-A1 TITANIUM DIOXIDE POWDER AND COSMETIC FORMULATED THEREWITH Shiseido Company Ltd. (JP) 2018-10-31 EP disclosed
CN-104853732-B Water-in-oil type emulsified composition 株式会社资生堂 2017-09-22 CN disclosed
CN-104853732-B Water-in-oil type emulsified composition 株式会社资生堂 2017-09-22 CN disclosed
US-9486755-B2 Production method of a powder cosmetic SHISEIDO COMPANY LTD. (JP) 2016-11-08 US disclosed
CN-104853732-A Water-in-oil type emulsified composition SHISEIDO CO LTD 2015-08-19 CN disclosed
WO-2014069403-A1 WATER-IN-OIL EMULSION COMPOSITION 株式会社 資生堂 (JP) 2014-05-08 WO disclosed
EP-2233126-B1 PROCESS FOR PRODUCING POWDERY COSMETIC PREPARATION SHISEIDO CO LTD (JP) 2012-08-15 EP disclosed
US-20120034281-A1 Solid Powder Cosmetic And Method For Producing The Same SHISEIDO COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2415457-A1 SOLID POWDER COSMETIC AND METHOD FOR PRODUCING THE SAME Shiseido Company, Ltd. (JP) 2012-02-08 EP disclosed
US-20100266519-A1 Production Method Of A Powder Cosmetic SHISEIDO COMPANY LTD. (JP) 2010-10-21 US disclosed
EP-2233126-A1 PROCESS FOR PRODUCING POWDERY COSMETIC PREPARATION Shiseido Company, Ltd. (JP) 2010-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034281-A1 Solid Powder Cosmetic And Method For Producing The Same CUTA, ACR, ZKSCAN2 TSHR 1734/4885THRB 3369/4885
US-20100266519-A1 Production Method Of A Powder Cosmetic CUTA, PRKDC, CROCC TSHR 926/4885THRB 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.