Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369805 | 0.88 | CYP4A11 (0.50) | RARBFFAR1FFAR4MEN1KMT2A | |
| SCHEMBL370894 | 0.84 | RARB (0.46) | RARBMEN1KMT2AALDH1A1SLC16A3 | |
| SCHEMBL29488620 | 0.82 | RARB (0.52) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL29488619 | 0.82 | RARB (0.52) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL15741313 | 0.82 | RARB (0.52) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL7147421 | 0.80 | RARB (0.60) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8769252 | 0.80 | RARB (0.60) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL10596391 | 0.80 | RARB (0.60) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8769316 | 0.80 | RARB (0.60) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8769281 | 0.80 | RARB (0.60) | RARBMEN1KMT2AALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |