Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365325 | 0.88 | RARB (0.53) | FFAR1FFAR4MEN1KMT2ANPC1 | |
| SCHEMBL370976 | 0.85 | EGFR (0.50) | CYP4A11CYP4F2EGFRPTGS2TDP1 | |
| SCHEMBL4664597 | 0.79 | EGFR (0.60) | CYP4A11CYP4F2EGFRPTGS2MEN1 | |
| SCHEMBL35683 | 0.76 | RARB (0.58) | CYP4A11CYP4F2EGFRPTGS2FAAH | |
| SCHEMBL27621631 | 0.76 | EGFR (0.56) | EGFRPTGS2MEN1KMT2ANPC1 | |
| SCHEMBL371299 | 0.75 | FFAR1 (0.41) | TDP1FFAR1FFAR4 | |
| SCHEMBL6261633 | 0.74 | CYP4A11 (0.60) | CYP4A11CYP4F2NPC1RAB9AALDH1A1 | |
| SCHEMBL16010982 | 0.74 | CYP4A11 (0.53) | CYP4A11CYP4F2FAAHMEN1KMT2A | |
| SCHEMBL3748237 | 0.73 | EGFR (0.63) | EGFRPTGS2TDP1MEN1KMT2A | |
| SCHEMBL10458005 | 0.73 | PTGS2 (0.76) | EGFRPTGS2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |